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It was discovered that naltrexone and bupropion combined, which might be marketed down the road as Contrave, provide better weight loss results than diet and exercise alone.

Using two separate drugs to lose weight can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the people who go through it you need to err on the side of caution and let the FDA do its job and demand some research be done so that the public understands the side effects and risks of the medications before we take them. Keep in mind that drug companies have been in business to make money and that they would say everything to keep people on their medications.

Researchers discovered that participants taking this drug for any year, lost excess weight within one month and have kept the load off during the entire 56 weeks in the study. Contrave is a combination in the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which are made up of multiple active ingredient, which might make them far better and safer.

Combo-pilling may be the newest fad or in addition to this the newest into the future under scrutiny and thus it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular is the fact that as of right now there aren't any long term prescription weightloss pills that have been approved by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug could also raise blood pressure level and pulse rate, and mustn't be used in individuals with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise hypertension and heartrate and must stop used in patients with uncontrolled high blood pressure levels, and also by you aren't heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients having a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients on the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.


The most common unwanted effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.