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Experts from Brigham Young University in Utah found that addiction results from an 'overcorrection' inside brain, a PsychCentral report said.

Using two separate drugs to lose weight can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the people that go through it one should err assisting caution and allow FDA do its job and demand some research be done so your public understands the side effects and risks of the medications before we take them. Keep in mind that drug companies come in business to generate money and that they would say anything to keep people on their own medications.

Researchers found out that participants taking this drug to get a year, lost weight within 4 weeks and have kept the body weight off during the entire 56 weeks in the study. Contrave is really a combination from the drugs naltrexone and bupropion, which usually reflect a fresh trend of weight-loss drugs which might be made up of more than one active ingredient, that might make them more potent and safer.

Combo-pilling is the newest fad or in addition to this the newest in the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is now popular may be the fact that at the time of right now there are no long term prescription weightloss pills that have been licensed by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures can be a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug could also raise blood pressure level and pulse rate, and shouldn't be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure level and pulse rate and must 't be used in patients with uncontrolled high blood pressure levels, as well as by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients using a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients to the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking.


Approving a drug using this many potentially lethal negative effects is inconsistent using the mission statement in the FDA. The power from the drug manufacturing lobby is blatantly evident inside approval of many drugs requiring 'post-marketing' studies which are clearly significant to overall drug safety within the US.